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Meropenem
Cas No.: 96036-03-2
Standard: USP 28, 29,30
Chemical Name: (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimeth-ylamino)carbonyl]-3-pyrrolidinyl] thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2- carboxylic acid
Pure powder or mixed with Sodium Carbonate
Typical COA for reference:
APPEARANCE
Almost white or yellowish power
Conformed
Identification
Complies with the test
Confirmed
PH
7.3-8.3
7.7
Loss in drying
9.0%-12.0%
10.1%
Related substances
Nmt 0.8% the impurity with a retention time of about 0.45 relative to that of Meropenem and NMT 0.6% of the impurity with 1.90 relative
conformed
Particulate matter
Meets the requirement of the test
Conformed
Content of sodium
1000mg of meropenem contain NLT 90.2 mg of sodium
conformed
Content of sodium carbonate
Between 16.8%-25.1% calculated on meropenem basis
20.8%
Assay on anhydrous basis
It contains not less than 78.0 percent of meropenem
81.6%
Bacterial xxxxx
0.12EU max
Conformed
Sterility
Complies with the test
conformed
Dasatinib (BMS-354825) is a novel, oral, potent, multi-targeted kinase inhibitor of Bcr-Abl and Src family kinases (SFK) and is a promising cancer therapeutic agent. Preclinical data indicate that dasatinib is 325-fold more potent than imatinib against cells expressing wild-type Bcr-Abl, and that dasatinib is active against 18 of 19 Bcr-Abl mutations known to cause imatinib resistance.
Chemical Name: N -(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)- 1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazole carboxamide monohydrate
CAS No.: [863127-77-9]
Molecular Formula: C 22H 26ClN7O2S.H 2 O
Molecular Weight: 506.02
Description:Off-white to pale yellow power .
Solubility: Insoluble in water, slightly soluble in methanol and ethanol.
Related substances:Any single impurities: NMT0.5%; Total impurities: NMT1.0%
Assay(HPLC):min 99%
Product name:Meropenem trihydrate
CAS : 119478-56-7
Molecular Formula: C17H25N3O5S
Molecular Weight: 383.46
Characters: A white or slightly yellowish crystalline powder;odorless;bitterness.water: 11.4%~13.4%
Related substances: Single impurity<0. 5%;Impurity total<1.5%
Assy(HPLC): 98%
Product name:?methylazetidin-2-one(4BMA)
CAS : 90776-58-2
Molecular Formula: C14H27NO4Si
Molecular Weight: 301.45
Characters: A white crystalline powder;
.water(K.F): not more than0.2%
Assy(HPLC): not less than 98%
Product name:MAP
CAS : 90776-59-3
Molecular Formula: C29H27N2O10P
Molecular Weight: 594.52
Characters: A white to off white crystalline powder;
.water(K.F): not more than0.1%
Assy(HPLC): not less than 98%
Product name:Meropenem Side chain
CAS : 96034-64-9
Molecular Formula: C15H19N3O5S
Molecular Weight: 353.40
.water(K.F): not more than0.1%
Assy(HPLC): not less than 98%
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